Skilled assassin Will Robie is asked by the U.S. government to track down fellow assassin Jessica Reel, who has gone rogue, but during his pursuit of Reel, Robie realizes that her betrayal may be concealing a larger threat that could impact the whole world.

Earl Fontaine, a terminally ill Alabama death row prisoner, plans one last killing that will personally affect Robie and his fellow agent, Jessica Reel. Meanwhile Evan Tucker, the head of the CIA, recommends Robie and Reel for a mission to assassinate a foreign leader.

Will Robie returns home from a mission overseas to discover that his boss--codenamed Blue Man--has vanished. His last known location was in remote Colorado, and there have been no other sightings or communications since. But there is violence brewing in this small town, and Robie and his sometime-partner Jessica Reel will be lucky if they make it out alive, with or without Blue Man.

Will Robie und seine Partnerin Jessica Reel, die zwei besten Profikiller ihres Landes, erhalten vom Präsidenten einen heiklen Auftrag: Sie sollen Nordkoreas unberechenbaren Führer ausschalten. Während sie sich auf ihre Mission vorbereiten, wird Jessica von den Geistern ihrer Vergangenheit eingeholt, die alle bedrohen, die ihr nahestehen. Doch damit nicht genug, denn plötzlich taucht ein neuer, unbekannter Feind auf: eine Frau mit eigener Abschussliste....